Center for Injury Research and Prevention

Carlyn Patterson Gentile, MD, PhD

Carlyn Patterson Gentile CIRP
CIRP Senior Fellow

Carlyn Patterson Gentile, MD, PhD is a Senior Fellow at the Center for Injury Research and Prevention at Children’s Hospital of Philadelphia (CHOP) and an Attending Physician in the Division of Neurology at CHOP. Dr. Patterson Gentile is also an Instructor of Neurology at the University of Pennsylvania.

Dr. Patterson Gentile's research focuses on exploring biomarkers to identify children and adolescents at risk for developing chronic post-traumatic headache following concussion, which is associated with prolonged recovery, to allow for earlier intervention. She is interested in understanding the symptomatic and pathophysiologic overlap between post-traumatic headache and migraine in the pediatric population. Her biomarker research includes longitudinally measuring visually-evoked potentials (VEPs) in children and adolescents following concussion who develop chronic post-traumatic headache compared to those who recover. Dr. Patterson Gentile is also interested in measuring calcitonin gene-related peptide (CGRP), an inflammatory neuropeptide that is important in migraine pathogenesis, following concussion.

She holds a Bachelor of Arts in Neuroscience from Hamilton College and an MD and PhD in Neuroscience from the Albert Einstein College of Medicine. Dr. Patterson Gentile is board-certified in Child Neurology. She can be reached at pattersonc@email.chop.edu.

Research Interests

concussion biomarkers, symptomatic and pathophysiologic overlap between post-traumatic headache and migraine