Carlyn Patterson Gentile, MD, PhD
Senior Fellow

Dr. Patterson Gentile is an Attending Physician in the Division of Neurology at Children's Hospital of Philadelphia and a Senior Fellow at the Center for Injury Research and Prevention.


Carlyn Patterson Gentile, MD, PhD is a Senior Fellow at the Center for Injury Research and Prevention at Children’s Hospital of Philadelphia (CHOP) and an Attending Physician in the Division of Neurology at CHOP. Dr. Patterson Gentile is also an Instructor of Neurology at the University of Pennsylvania.

Dr. Patterson Gentile's research focuses on exploring biomarkers to identify children and adolescents at risk for developing chronic post-traumatic headache following concussion, which is associated with prolonged recovery, to allow for earlier intervention. She is interested in understanding the symptomatic and pathophysiologic overlap between post-traumatic headache and migraine in the pediatric population. Her biomarker research includes longitudinally measuring visually-evoked potentials (VEPs) in children and adolescents following concussion who develop chronic post-traumatic headache compared to those who recover. Dr. Patterson Gentile is also interested in measuring calcitonin gene-related peptide (CGRP), an inflammatory neuropeptide that is important in migraine pathogenesis, following concussion.

BA, Hamilton College (Neuroscience), 2006

PhD, Albert Einstein College of Medicine (Neuroscience), 2012

MD, Albert Einstein College of Medicine, 2014

Senior Fellow, Center for Injury Research and Prevention, Children's Hospital of Philadelphia

Attending Physician, Division of Neurology, Children's Hospital of Philadelphia

Instructor of Neurology, University of Pennsylvania

Member, American Academy of Pediatrics

Committee Member, American Academy of Pediatrics Section on Neurology

Member, American Academy of Neurology

Member, American Headache Society

Member, Child Neurology Society

Patterson-Gentile C, Aguirre GKarl. A Neural Correlate of Visual Discomfort From Flicker. J Vis. 2020;20(7):11.

Patterson-Gentile C, Szperka CL. The Changing Landscape of Pediatric Migraine Therapy: A Review. JAMA Neurol. 2018;75(7):881-887.

Contact Information
Colket Translational Research Building, 3501 Civic Center Blvd., PA 19104