Center for Injury Research and Prevention

Christopher Bonafide, MD, MSCE

Christopher Bonafide, MD CIRP
CIRP Senior Fellow

Christopher Bonafide, MD, MSCE is a Senior Fellow at the Center for Injury Research and Prevention at Children’s Hospital of Philadelphia (CHOP) and an Attending Physician at CHOP. Dr. Bonafide is also the Research Director of General Pediatric Hospital Medicine at CHOP, an Investigator within the Center for Pediatric Clinical Effectiveness, and an Assistant Professor of Pediatrics at the University of Pennsylvania.

Dr. Bonafide's research focuses on discovering the best ways to identify deteriorating patients in the hospital and the best mechanisms to respond to those patients. He is also interested in identifying unintended consequences of interventions intended to improve patient safety. Alarm fatigue from bedside monitors and alert fatigue from electronic health records are two examples. Dr. Bonafide has investigated these areas using a wide range of study designs and methods, most of which are relevant to clinical informatics.

Dr. Bonafide also co-directs a pediatric hospital medicine research fellowship at CHOP funded by the National Institutes of Health, serves as an Associate Editor of the Journal of Hospital Medicine, and is on the editorial board for the new journal, Pediatric Quality and Safety.

Dr. Bonafide holds a Bachelor of Arts in Psychology from Colby College, an MD from the Pennsylvania State University College of Medicine, and an MSCE in Clinical Epidemiology from the University of Pennsylvania. He is board-certified in General Pediatrics and Clinical Informatics in the United States. Dr. Bonafide can be reached at

Research Interests

Clinical epidemiology, biostatistics, clinical informatics, systems engineering, and implementation science